Colonoscopy found that the inside of the large intestine was black, what should I do? Doctors remind patients that pigmentation may occur due to chronic constipation or long-term use of stimulant laxatives, such as senna and rhubarb derivatives, but generally the melanin will slowly disappear as long as the laxatives are stopped. If you are troubled by constipation, relying on laxatives will make the constipation worse. It is recommended to seek medical advice as soon as possible and prescribe the right medicine.

Melanosis coli (also known as melanosis coli) is a disease caused by pigmentation of the large intestine wall. Long-term use of laxatives causes damage to intestinal cells. The damaged cells appear dark and will be phagocytosed by macrophages, so the intestinal mucosa will appear dark brown. This manifestation is a benign disease without any pain, and constipation is the main symptom.
If you have constipation, you can arrange physical examination, digital anal examination, blood draw, abdominal X-ray, fecal occult blood test,Colonoscopyetc., to identify the condition causing constipation.
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